The Davies Lab broadly explores microbial behavior important for improving human health and well-being. Through our research, we develop a mechanistic understanding of the processes controlling the ability of microbes to engage with humans, and engineer biologics and synthetic cell-based systems to manipulate this interface.

Research is in progress in the following areas:

  • Exploring the scope of peptide sequence and structural space with antimicrobial and immune modulatory action.
  • Developing peptide-based inhibitors of essential bacterial functions.
  • Engineering multi-functional antibodies to control microbe-microbe and microbe-host interactions.
  • Studying interactions between skin, commensals, and pathogens.
  • Building synthetic cell-based systems for high throughput peptide/protein screening and delivery.
  • Engineering synthetic microbes to manipulate human health and performance.
  • Characterizing peptides and proteins as reversible and degradable materials.